埃默里大学对亚特兰大大都会区1100多名居民进行的一项新研究表明，空气污染直接导致大脑退化，增加患阿尔茨海默病的风险。 --埃默里大学的一项新研究发现，暴露在高水平空气污染中的成年人患阿尔茨海默病的风险增加。 在一项针对1113名年龄在45-75岁之间的参与者的研究中，研究人员发现阿尔茨海默病的阳性生物标志物，特别是在家中暴露于环境和交通相关空气污染的参与者的脑脊液中的淀粉样斑块。 这项研究发表在《环境健康展望》上，是同类研究中规模最大的一项，增加了越来越多的证据，包括埃默里大学最近的其他研究，这些研究表明空气污染直接导致大脑退化。 专家们所说的“综合来看，我们最近的研究代表了光谱的两端。 在我们之前的研究中，我们在尸检队列中显示了住宅暴露在空气污染中与阿尔茨海默氏症相关的大脑变化之间的关系，现在，我们在一项对平均年轻15岁且认知健康的成年患者的研究中发现了类似的结果。 这一点很重要，因为它表明，即使在我们真正患上阿尔茨海默病之前几十年，住宅空气污染也会对我们的大脑产生负面影响。 这表明暴露和机会都是一个敏感的时期，因为这是预防策略和干预措施最有效的时期。 该研究的主要作者、埃默里大学罗林斯公共卫生学院流行病学系助理教授，博士。 “我们知道空气污染通常对人类健康有害，包括大脑健康。 通过显示与脑脊液中淀粉样蛋白水平的关系，这项研究表明，空气污染可能会增加患阿尔茨海默病的风险。 另一方面，通过清理我们的环境，我们也可以帮助减轻阿尔茨海默病的负担。 james lah，医学博士/博士，emory健康大脑研究的首席研究员，emory医学院神经病学系副教授。 减少空气污染暴露的方法当当地空气质量指数报告空气质量较差时，限制时间并避免户外体育活动。 如果你必须在空气质量差的日子外出，可以考虑戴口罩，比如n95口罩。 做其他已知的有助于降低阿尔茨海默病风险的事情，包括疾病控制和预防中心的建议：练习健康饮食。 进行有规律的体育活动。 预防/管理高血压和血糖。 戒烟并避免过量饮酒。 充足的睡眠。
a new emory university study of more than 1,100 residents of the atlanta metropolitan area suggests that air pollution directly contributes to degeneration in the brain, increasing the risk of developing alzheimers disease.— getty imagesa new emory university study has found that adults exposed to high levels of air pollution were at an increased risk of developing alzheimer’s disease.in a study of 1,113 participants between the ages of 45-75 from the emory healthy brain study, all of whom were from the atlanta metropolitan area, the researchers found positive biomarkers of alzheimer’s diseasespecifically amyloid plaques in the cerebrospinal fluid of participants who were exposed to ambient and traffic-related air pollution at their homes.this study, which was published in environmental health perspectives, was the largest of its kind and adds to the growing body of evidenceincluding other recent studies from emory universitythat suggests air pollution directly contributes to degeneration in the brain.what the experts say“together, our recent studies represent both ends of the spectrum. in our previous study we showed associations between residential exposure to air pollution and alzheimer’s-related changes in the brain in an autopsy cohort and now, we found similar results in a study of living adults who were on average 15 years younger and cognitively healthy. this is important because it shows that residential air pollution can negatively affect our brain even decades before we actually develop alzheimer’s disease. this points to a sensitive time period for both exposure and opportunity, because that is time when prevention strategies and interventions are most effective.” anke huels, phd, the study’s lead author and an assistant professor in the department of epidemiology at emory’s rollins school of public health.“we know that air pollution is generally bad for human health, including brain health. by showing a relationship to levels of the amyloid protein in the cerebrospinal fluid, this study suggests that air pollution might increase the risk of developing alzheimer’s disease. the flip side of that is that by cleaning up our environment, we might also help reduce the burden of alzheimer’s disease.” james lah, md/phd, principal investigator of the emory healthy brain study and an associate professor in the department of neurology at emory’s school of medicine.ways to reduce air pollution exposurelimit time and avoid physical activity outside on days when your local air quality index reports air quality is poor.if you must be outside on poor air quality days, consider wearing a mask, such as an n95 mask.do other things known to help reduce alzheimer’s risk, including these tips from the centers for disease control and prevention:practice eating a healthy diet.engage in regular physical activity.prevent/manage high blood pressure and blood sugar.quit smoking and avoid excessive alcohol consumption.get plenty of sleep.
