澳大利亚悉尼大学的研究人员对3万人进行了近8年的跟踪调查，发现在晚上进行大部分日常体育活动对肥胖者的健康益处最大。 澳大利亚悉尼大学的研究人员对3万人进行了近8年的跟踪调查，发现在晚上进行大部分日常体育活动对肥胖者的健康益处最大。 研究人员利用可穿戴设备的数据，按早上、下午或晚上对参与者的体力活动进行分类，发现那些在下午6点到午夜之间进行了大部分有氧中等强度到剧烈体力活动的人，过早死亡和死于心血管疾病的风险最低。 人们在晚上进行中等强度到剧烈体力活动的频率（以短时间达到或超过三分钟为单位）似乎也比他们每天的体力活动总量更重要。 这项由该大学charlesperkins中心的研究人员领导的研究发表在今天的《糖尿病护理》杂志上。 悉尼大学运动生理学讲师angelo sabag博士说：“由于许多复杂的社会因素，大约三分之二的澳大利亚人超重或肥胖，这使他们患心脏病发作、中风和过早死亡等主要心血管疾病的风险更大。”。 “运动决不是解决肥胖危机的唯一方法，但这项研究确实表明，那些能够在一天中的特定时间计划活动的人可能会最好地抵消其中的一些健康风险。 “较小的临床试验也显示出类似的结果，然而，这项研究中的大量参与者数据，对体力活动和过早死亡等艰难结果的客观测量，使这些发现具有重要意义。 联合第一作者matthew ahmadi博士也强调，这项研究不仅仅是追踪结构化运动。 相反，研究人员专注于追踪3分钟或更长时间内持续有氧运动的mvpa，因为之前的研究表明，与较短的（非有氧）运动相比，这种类型的运动、血糖控制和降低心血管疾病风险之间有很强的关联。 悉尼大学charlesperkins中心的国家心脏基金会博士后研究员ahmadi博士说：“我们没有区别对待我们追踪的活动类型，它可以是从力量行走到爬楼梯的任何活动，但也可以包括有组织的锻炼，如跑步、职业劳动，甚至大力打扫房子。”。 虽然是观察性的，但这项研究的结果支持了作者最初的假设，即基于先前的研究，患有糖尿病或肥胖的人，如果在深夜已经对葡萄糖不耐受，可以通过在晚上进行体育活动来抵消一些不耐受和相关的并发症。 这项研究是如何进行的？研究人员使用了英国生物库的数据，包括29836名40岁以上的肥胖成年人，其中2995名参与者也被诊断为2型糖尿病。 参与者被分为早上、下午和晚上的mvpa，这是基于他们在研究开始时通过手腕加速计测量的大部分有氧mvpa，该加速计在7天内每天24小时连续佩戴。 然后，研究小组将健康数据（来自苏格兰国家卫生服务局和国家记录）联系起来，追踪参与者7年的健康轨迹。 9年。 在此期间，他们记录了1425例死亡、3980例心血管事件和2162例微血管功能障碍事件。 为了限制偏差，研究人员考虑了年龄、性别、吸烟、饮酒、水果和蔬菜消费、久坐时间、总mvpa、教育程度、药物使用和睡眠时间等差异。 他们还排除了已有心血管疾病和癌症的参与者。 研究人员表示，研究随访的时间和额外的敏感性分析增强了他们研究结果的强度，然而，由于观察设计的原因，他们不能完全排除潜在的反向因果关系。 这可能是由于潜在的或未诊断的疾病，一些参与者的有氧运动mvpa水平较低。 为什么这项研究很重要？查尔斯·珀金斯中心麦肯齐可穿戴设备研究中心主任、该论文的资深作者emmanuel stamatakis教授表示，可穿戴设备领域的复杂研究为最有益于健康的活动模式提供了巨大的见解。 斯塔马塔基斯教授说：“对于这一领域的研究人员和从业者来说，这是一个非常激动人心的时刻，因为可穿戴设备捕获的数据使我们能够以非常高的分辨率检查身体活动模式，并将研究结果准确地转化为在医疗保健中发挥重要作用的建议。”。 “虽然我们需要做进一步的研究来确定因果关系，但这项研究表明，体育活动的时间安排可能是未来肥胖和2型糖尿病管理以及一般预防性医疗保健建议的重要组成部分。 声明：这项研究是使用英国生物库资源进行的，申请号为25813。 这项研究是由澳大利亚国家卫生和医学研究委员会研究者资助的，并由澳大利亚国家健康基金会博士后研究金资助。 作者没有潜在的利益冲突需要报告。
undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers from the university of sydney, australia who followed the trajectory of 30,000 people over almost 8 years.undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers from the university of sydney, australia who followed the trajectory of 30,000 people over almost 8 years.using wearable device data to categorise participant’s physical activity by morning, afternoon or evening, the researchers uncovered that those who did the majority of their aerobic moderate to vigorous physical activity– the kind that raises our heartrate and gets us out of breath– between 6pm and midnight had the lowest risk of premature death and death from cardiovascular disease.the frequency with which people undertook moderate to vigorous physical activity (mvpa) in the evening, measured in short bouts up to or exceeding three minutes, also appeared to be more important than their total amount of physical activity daily.the study, led by researchers from the university’s charles perkins centre is published in the journal diabetes care today.“due to a number of complex societal factors, around two in three australians have excess weight or obesity which puts them at a much greater risk of major cardiovascular conditions such as heart attacks and stroke, and premature death,” said dr angelo sabag, lecturer in exercise physiology at the university of sydney.“exercise is by no means the only solution to the obesity crisis, but this research does suggest that people who can plan their activity into certain times of the day may best offset some of these health risks.”smaller clinical trials have shown similar results, however the large scale of participant data in this study, the use of objective measures of physical activity and hard outcomes, such as premature death, makes these findings significant.joint first author dr matthew ahmadi also stressed that the study did not just track structured exercise. rather researchers focused on tracking continuous aerobic mvpa in bouts of 3 minutes or more as previous research shows a strong association between this type of activity, glucose control and lowered cardiovascular disease risk compared with shorter (non-aerobic) bouts.“we didn’t discriminate on the kind of activity we tracked, it could be anything from power walking to climbing the stairs, but could also include structured exercise such as running, occupational labour or even vigorously cleaning the house,” said dr ahmadi, national heart foundation postdoctoral research fellow at the charles perkins centre, university of sydney.while observational, the findings of the study support the authors original hypothesis, which is the idea – based on previous research - that people living with diabetes or obesity, who are already glucose intolerant in the late evening, may be able to offset some of that intolerance and associated complications, by doing physical activity in the evening.how was the study conducted?the researchers used data from uk biobank and included 29,836 adults aged over 40 years of age living with obesity, of whom 2,995 participants were also diagnosed with type 2 diabetes.participants were categorised into morning, afternoon of evening mvpa based on when they undertook the majority of their aerobic mvpa as measured by a wrist accelerometer worn continuously for 24 hours a day over 7 days at study onset.the team then linked health data (from the national health services and national records of scotland) to follow participants health trajectory for 7.9 years. over this period they recorded 1,425 deaths, 3,980 cardiovascular events and 2,162 microvascular disfunction events.to limit bias, the researchers accounted for differences such as age, sex, smoking, alcohol intake, fruit and vegetable consumption, sedentary time, total mvpa, education, medication use and sleep duration. they also excluded participants with pre-existing cardiovascular disease and cancer.the researchers say the length of the study follow-up and additional sensitivity analysis bolster the strength of their findings however, due to the observational design, they cannot completely rule out potential reverse causation. this is the possibility that some participants had lower aerobic mvpa levels due to underlying or undiagnosed disease.why is this study important?professor emmanuel stamatakis, director of the mackenzie wearables research hub at the charles perkins centre and senior author on the paper, said the sophistication of studies in the wearables field is providing huge insights into the patterns of activity that are most beneficial for health.“it is a really exciting time for researchers in this field and practitioners alike, as wearable device-captured data allow us to examine physical activity patterns at a very high resolution and accurately translate findings into advice that could play an important role in health care,” said professor stamatakis. “while we need to do further research to establish causal links, this study suggests that the timing of physical activity could be an important part of the recommendations for future obesity and type 2 diabetes management, and preventive healthcare in general.”declaration: this research was conducted using the uk biobank resource under application 25813. this study was funded by an australian national health and medical research council investigator grant and the national health foundation of australia postdoctoral fellowship. the authors have no potential conflicts of interest to report.
