这一战略合作伙伴关系将使悉尼大学在推进纳米医学、基因疗法以及疾病的早期检测、治疗和预防方面处于国际领先地位。 悉尼大学将与布鲁克建立新的合作伙伴关系，为纳米医学的创新提供动力，成为两台原子力显微镜的所在地。 作为推进纳米医学的双边承诺的一部分，布鲁克将提供资源支持由戴维·马丁内斯·马丁博士领导的合作研究。 图片由bruker bioafm提供。 想象一下，在未来，像单个细胞或分子簇这样微小的样本可以进行医学诊断，并根据你的身体量身定制治疗方法。 它被称为精准医疗，是定制医疗服务的极致，而且即将问世。 悉尼大学的研究人员在精准医学方面迈出了重要的一步，该大学今天宣布与世界领先的高性能科学仪器制造商布鲁克建立为期五年的研究合作关系。 根据合作关系，该大学将获得两台由布鲁克公司制造的原子力显微镜，以增加其世界级的研究设施。 新一代显微镜将于本月安装。 该系统是澳大利亚第一个此类系统，可对活体生物样本进行最高分辨率成像，可视化动态分子机制，并量化细胞和生物分子的相互作用。 先进的自动化能力使其成为生物医学和临床前研究的理想选择。 作为该大学核心研究设施的一部分，这些显微镜将可供行业合作伙伴租用，并用于支持研究。 悉尼大学生物医学工程高级讲师davidmartinez-martin博士是这一合作关系背后的驱动力。 他说：“学术界和工业界之间的这种真正的、创新的合作对于应对健康及其他领域的社会挑战至关重要。 纳米技术创新大卫•马丁内斯•马丁博士是一位颇有成就的创新者，他拥有19项已获授权的专利，其中17项已获许可或转让给工业界。 图片：悉尼大学杰出的物理学家和创新者martinez-martin博士是全球公认的新技术发明者，在原子力显微镜领域与布鲁克有着长期的合作。 他说：“大约十年前，我开始与布鲁克的团队合作，以提高原子力显微镜的性能。 与工业界合作使我接触到了学术界之外的观点，这些观点对发展有影响力的研究非常有益，并使我作为一名研究人员和创新者获得了极大的丰富。 悉尼大学对这一合作伙伴关系的投资将促进martinez-martin博士的工作，并使悉尼大学在推进纳米医学、基因疗法以及疾病的早期检测、治疗和预防方面处于国际领先地位。 作为合作的一部分，brucker将提供资源支持由davidmartinez-martin博士推动的纳米技术合作项目。 原子力显微镜使科学家能够在纳米级甚至逐个分子地分析和操纵活细胞和材料。 它还可以识别一系列传染病和癌症的新生物标志物或生物特征。 它通过使用激光测量显微镜传感器与十亿分之一米规模的样本的物理相互作用来实现这一点。 “很高兴看到我的工作促成了更大的合作伙伴关系，以支持纳米医学和原子力显微镜的高级研究。 martinez-martin博士说：“我感谢我的大学同事和布鲁克，感谢他们使这种伙伴关系成为现实。”。 副校长（研究基础设施）simonringer教授是该大学战略伙伴关系政策的设计师，他说：“这些能力将把我们的社区带到纳米医学和纳米制造的前沿，这是下一代精准药物的基础。 这种伙伴关系在健康进步方面的社会效益潜力是令人印象深刻和兴奋的。 辅助噬菌体phi29的研究与开发。 它是一种感染细菌的病毒。 它也是已知最小的病毒之一。 它的赤道直径（宽度）约为45纳米。 davidmartinez-martin用原子力显微镜在液体环境中获取图像。 新的原子力显微镜将被安置在悉尼大学坎伯当校区内的悉尼显微镜和微量分析中心，这是一个开放获取的核心研究设施，马丁内斯·马丁博士是该中心的副主任。 悉尼显微镜和微量分析拥有一系列纳米技术仪器，是该大学八个向行业使用和合作开放的核心研究设施之一。 悉尼显微镜与微量分析中心主任、副教授菲利普·布雷特说：“将这些首先植入澳大利亚的显微镜植入我们的核心研究设施，将确保任何需要它们的研究人员都能获得它们，为一系列不同项目和科学学科中令人兴奋的本土发现铺平道路。”。 martinez-martin博士对原子力显微镜所提供的潜力感到兴奋。 “作为一个有着发明家和创新者记录的人，我可以自信地说，与布鲁克的合作将加强我们的健康和纳米技术创新生态系统。 医学和纳米技术的未来是令人兴奋的，这种合作关系将使我们能够创造它。 背景悉尼显微镜和微量分析（smm）是悉尼大学的八个核心研究机构之一。 它为研究人员和工业界提供了高端显微镜基础设施和相关专业知识，使人们能够深入了解材料如何在活细胞、分子、晶体甚至单个原子的尺度上工作。 smm是世界上最大、最全面的同类设施之一。 它是显微镜澳大利亚的一个节点，显微镜澳大利亚是一个由澳大利亚政府的国家合作研究基础设施战略（ncris）支持的大学显微镜设施联盟。 davidmartinez-martin博士是一位物理学家和创新者，拥有19项授权专利（18项为主要发明人，1项为共同主要发明人），其中17项已获得许可或转让给工业。 他以发明一种名为皮天平的商业技术而闻名，该技术可以实时测量活细胞的质量。 2022年，他被世界知识产权组织（wipo）评为杰出的年轻变革者。 simonringer教授是悉尼大学的副校长（研究基础设施），领导该大学在研究基础设施、研究技术服务和研究空间管理方面的战略、政策和建议。 布鲁克是世界领先的分析仪器、诊断解决方案和纳米分析工具制造商，为细胞生物学、临床前成像和分子病理学研究提供高性能系统。 bruckerbioafm开发和制造原子力显微镜（afm）和光镊子，特别关注在生物医学和生命科学研究中的应用。 bruckerbioafm开发和制造原子力显微镜（afm）和光镊子，特别关注在生物医学和生命科学研究中的应用。the strategic partnership will place the university of sydney in a leading position internationally to advance nanomedicine, gene therapies and the early detection, treatment and prevention of disease.the university of sydney will become home to two atomic force microscopes under a new partnership with bruker to power innovation in nanomedicine. bruker will provide resourcing to support collaborative research led by dr david martinez martin as part of a bilateral commitment to advancing nanomedicine. image courtesy of bruker bioafm.imagine a future where samples as tiny as single cells or clusters of molecules can lead to medical diagnoses, and treatments are tailored specifically to your body. known as precision medicine, it’s the ultimate in bespoke health service—and it’s on the horizon. researchers at the university of sydney have taken a significant stride forward in precision medicine, with the university today announcing a five-year research partnership with bruker, a world-leading manufacturer of high-performance scientific instruments. under the partnership, the university will acquire two atomic force microscopes made by bruker to add to its world-class research facilities. the new-generation microscopes are being installed this month. the first of their kind in australia, the systems are customised to perform the highest resolution imaging of living biological samples, visualise dynamic molecular mechanisms and quantify cellular and biomolecular interactions. advanced automation capabilities make them ideal for biomedical and preclinical research.as part of the university’s core research facilities, the microscopes will be available for hire to industry partners and to support research.the driving force behind the partnership is dr david martinez martin, senior lecturer in biomedical engineering at the university of sydney. he said: “this kind of genuine, innovative collaboration between academia and industry is essential to address societal challenges in the area of health and beyond.” nanotechnology innovationdr david martinez martin is an accomplished innovator who holds 19 granted patents, 17 of which have been licensed or assigned to industry. image: university of sydneyan accomplished physicist and innovator, dr martinez martin is a globally recognised inventor of new technologies, and has had a long-standing collaboration with bruker in the atomic force microscopy area. he said: “i started collaborating with bruker’s team about a decade ago to boost the performance of atomic force microscopes. working with industry exposed me to perspectives outside of academia that are highly beneficial for developing impactful research and enriched me significantly as a researcher and innovator.” the university’s investment in the partnership will boost dr martinez martin’s work and place the university of sydney in a leading position internationally to advance nanomedicine, gene therapies and the early detection, treatment and prevention of disease. as part of the collaboration, bruker will provide resourcing to support collaborative nanotechnology projects driven by dr david martinez martin.atomic force microscopy allows scientists to analyse and manipulate live cells and materials at the nanoscale, even molecule by molecule. it can also enable the identification of new biomarkers, or biological signatures, of a range of infectious diseases and cancers. it does this by using a laser to measure the physical interaction of the microscope’s sensor with a sample at the scale of a billionth of a metre.“its great to see my work seeding a larger partnership to support advanced research in nanomedicine and atomic force microscopy. i’m grateful to my university colleagues and to bruker for making this partnership a reality,“ said dr martinez martin.professor simon ringer, pro vice chancellor (research infrastructure), an architect of the university’s strategic partnerships policy, said: “these capabilities will bring our community to the frontiers of nanomedicine and nanofabrication, which are the foundations of next-generation precision medicines. the potential for societal benefits from this partnership in terms of health advances are impressive and exciting.”research and development accessbacteriophage phi29. it is a virus that infects bacteria. it is also among the smallest viruses known. it has an equatorial diameter (width) of approximately 45 nanometres. image acquired in liquid environment with atomic force microscopy by dr david martinez-martin.the new atomic force microscopes will be housed on the university of sydney’s camperdown campus within sydney microscopy and microanalysis, an open-access core research facility where dr martinez martin is deputy director. sydney microscopy and microanalysis hosts a range of nanotechnology instrumentation and is one of eight core research facilities at the university that are open to industry usage and partnerships.director of sydney microscopy and microanalysis, associate professor filip braet, said: “embedding these first-in-australia microscopes within our core research facilities will ensure that they are available to any researchers who need them, paving the way for exciting homegrown discoveries across a range of different projects and scientific disciplines.” dr martinez martin is excited by the potential that the atomic force microscopes offer. “as someone with a track record as an inventor and innovator, i can confidently say that this partnership with bruker will strengthen our health and nanotechnology innovation ecosystems. the future of medicine and nanotechnology is exciting, and this partnership will empower us to create it.” backgroundsydney microscopy and microanalysis (smm) is one of eight core research facilities at the university of sydney. it provides researchers and industry with access to high-end microscopy infrastructure and related expertise, enabling insights into how materials work at the scale of living cells, molecules, crystals and even individual atoms. smm is one of the largest and most comprehensive facilities of its kind in the world. it is a node of microscopy australia, a consortium of university-based microscopy facilities supported by the australian government’s national collaborative research infrastructure strategy (ncris). dr david martinez martin is a physicist and innovator who holds 19 granted patents (18 as principal inventor and 1 as co-principal inventor), 17 of which have been licensed or assigned to industry. he is renowned for the invention of a commercial technology called picobalance, which measures the mass of living cells in real time. in 2022 he was distinguished as a leading young changemaker by the world intellectual property organisation (wipo).professor simon ringer is the university of sydney’s pro-vice-chancellor (research infrastructure) and leads the university’s strategy, policy and advice relating to research infrastructure, research technology services, and research space management. bruker is a world-leading manufacturer of analytical instrumentation, diagnostic solutions and nano-analysistools, providing high-performance systems for cell biology, preclinical imaging, and molecular pathology research. bruker bioafm develops and manufactures atomic force microscopes (afm) and optical tweezers, with a particular focus on applications in biomedical and life science research. .本文来源： 大学与Bruker签署精准医学研究合作伙伴关系
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