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新的医学成像设施将彻底改变研究和患者护理

(New medical imaging facility to revolutionise research and patient care)

2023-12-13

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澳大利亚国家全身宠物设施将推动癌症研究、神经系统疾病、心血管疾病和药物开发的进步,并减少扫描时间和辐射剂量,以改变患者护理。 澳大利亚国家全身正电子发射断层扫描设备今天在悉尼正式启用,为澳大利亚开放获取研究和临床应用提供了第一台全身正电子发射层析成像扫描仪。 该设施将推动癌症研究、神经系统疾病、心血管疾病和药物开发的进展,并减少扫描时间和辐射剂量,以改变患者护理。 这项耗资1500万美元的设施是悉尼大学、国家成像设施和悉尼北部地方卫生区的合作项目,旨在造福澳大利亚患者、临床医生、研究人员和行业合作伙伴。 西门子biobiovisionquadra位于皇家北岸医院,是核医学成像领域的革命性飞跃。 这种尖端设备能够在一次扫描中实现全面的全身成像,显著减少辐射暴露,并将扫描时间从20分钟缩短到3分钟,同时提供更高质量的图像。 该设施展示了当领先的机构联合起来提高医疗保健和研究能力时可以取得的成果。 副校长马克·斯科特教授同时扫描所有组织和器官的能力为全身生理学和器官之间的相互作用提供了其他临床成像技术无法提供的独特见解。 它为肿瘤学、神经科学、心脏病学、传染病和药物发现等广泛的医学应用提供了研究机会,包括探索复杂的人体生物学和多个器官相互作用的方式,如脑肠轴。 该设施是澳大利亚最灵敏的宠物扫描仪,专门用于研究,将成为临床试验和行业合作的关键工具。 对整个人体成像的能力使研究人员能够同时观察药物在所有器官中的吸收、积累和消除过程。 在有影响力的研究和临床研究中,减少辐射和扫描时间扩大了儿童等弱势群体的宠物成像选择。 它还鼓励健康人参与临床试验,并使患者能够反复扫描,以更好地了解疾病进展和治疗效果,拓宽医学研究的视野。 悉尼大学副校长兼校长markscott教授表示:“悉尼大学、国家成像中心和悉尼北部地方卫生区之间的合作,展示了合作伙伴关系在推动创新方面的力量。”。 “这个设施展示了当领先的机构联合起来提高医疗保健和研究能力时可以取得的成就。 我们今天不仅在改善患者的健康,而且还利用这项技术为未来快速追踪新发现。 澳大利亚国家全身宠物设施医疗成像游戏规则的改变者。 一项这样的研究正在研究催产素分子在输送给人类时是如何影响大脑和身体的。 催产素是大脑中指导社会行为的最重要的天然化学物质之一。 研究表明,服用该药可以提高社会理解力,并可能对精神分裂症和自闭症患者提供支持。 然而,催产素在哪里被吸收,以及它影响大脑和身体的回路,从而对人类产生影响,这是一个谜。 悉尼大学教授亚当·瓜斯特拉领导的一个团队将使用tb-pet扫描仪实时观察催产素经鼻内或静脉注射后对大脑和身体回路的影响。 这有可能改变人类社会行为生物学的基本知识,并可能导致一系列新的疗法。 新设施是悉尼成像的一部分,悉尼成像是悉尼大学生物医学成像核心研究设施。 作为一个具有全国意义的研究平台,它也是国家成像设施(nif)的旗舰,通过澳大利亚政府教育部的国家合作研究基础设施战略(ncris)。 澳大利亚国家成像机构管理委员会主席玛格丽特·哈丁教授表示,澳大利亚国家医学会对澳大利亚国家全身宠物设施的800万美元投资是迄今为止最大的一笔投资,也是澳大利亚在分子成像方面最大的单笔投资,支持了在减轻澳大利亚疾病负担方面具有高度优先地位的研究。 哈丁教授说:“该设施是一项独特的国家资产,将彻底改变澳大利亚吸引和支持研发新药和医疗产品的研究和工业进行临床试验的能力,以改善澳大利亚的健康状况。”。 澳大利亚国家全身宠物设施将在临床使用和研究之间的平等时间分配安排下运行,确保每周有五天向澳大利亚各地的所有研究人员开放。 悉尼北部地方卫生区首席执行官兼副教授anthonyschembri在谈到患者福利时说:“皇家北岸医院和悉尼北部地方医疗区在提供世界级的成像和护理以改善患者预后方面有着引以为傲的历史。 “我们非常荣幸能够主办这场澳大利亚首次患者可以获得世界级护理的活动,研究人员可以使用扫描仪进行临床研究,这可能会在未来转化为改善患者护理。 这所大学对新设施的贡献是由威廉·查普曼留下的遗产支撑的,他将大部分遗产作为礼物献给了悉尼大学癌症研究。 他的遗产将对癌症研究以及患者的生存和生活质量产生巨大影响。 悉尼大学副校长(研究)emma johnston教授,他说:“这项令人惊叹的医学成像技术的临床和研究安排,以及它位于皇家北岸医院繁忙的活动中心,将促进研究人员、医疗保健提供者、政策制定者和行业领袖之间的合作,以加快研究转译的创新。 “更多信息有关澳大利亚国家全身宠物设施的更多信息,包括研究用途的功能和预订,请访问悉尼成像网站。 图片:皇家北岸医院剪彩仪式,嘉宾包括:emma johnston、katie ockenden、mark scott(悉尼大学)、anthony schembri、alison zecchin(悉尼北部地方卫生区)、simon ringer、robyn ward(悉尼大学,悉尼)、margaret harding(国家影像机构)、steven meikle、rebeca gonzalez,dale bailey(皇家北岸医院)、sarah flaim(国家成像机构)、fernando calamante(悉尼大学)、heather gough(皇家北岸医疗机构)、paul蟑螂(皇家北岸卫生机构)、wotjek goscinski(国家成像机构)和trevor danos(悉尼北部地方卫生区)。 图片:皇家北岸医院剪彩仪式,嘉宾包括:emma johnston、katie ockenden、mark scott(悉尼大学)、anthony schembri、alison zecchin(悉尼北部地方卫生区)、simon ringer、robyn ward(悉尼大学,悉尼)、margaret harding(国家影像机构)、steven meikle、rebeca gonzalez,dale bailey(皇家北岸医院)、sarah flaim(国家成像机构)、fernando calamante(悉尼大学)、heather gough(皇家北岸医疗机构)、paul蟑螂(皇家北岸卫生机构)、wotjek goscinski(国家成像机构)和trevor danos(悉尼北部地方卫生区)。
the australian national total body pet facility will drive advancements in cancer studies, neurological disorders, cardiovascular disease and drug development, and reduce scanning time and radiation doses to transform patient care.the australian national total body pet facility officially opens in sydney today, delivering the first total body positron emission tomography (tb-pet) scanner for australia-wide open access research, as well as clinical use.the facility will drive advancements in cancer studies, neurological disorders, cardiovascular disease and drug development, and reduce scanning time and radiation doses to transform patient care.the $15 million facility is a collaborative venture between the university of sydney, the national imaging facility (nif) and northern sydney local health district, to benefit australian patients, clinicians, researchers and industry partners.located at royal north shore hospital, the siemens biograph vision quadra is a revolutionary leap forward in nuclear medical imaging. this cutting-edge device enables comprehensive whole-body imaging in a single scan, significantly reducing radiation exposure and cutting down scanning time from 20 minutes to as little as three, all while delivering higher-quality images.this facility shows what can be achieved when leading institutions join forces to advance healthcare and research capabilities.professor mark scott, vice-chancellorthe ability to scan all tissues and organs simultaneously offers unique insights into whole-body physiology and interactions between organs that no other clinical imaging technology can provide. it presents research opportunities across a wide range of medical applications, such as oncology, neuroscience, cardiology, infectious diseases, and drug discovery – including exploring complex human biology and the way multiple organs interact such as the brain-gut axis.the facility is australia’s most sensitive pet scanner dedicated to research, and will be a critical tool for clinical trials and industry collaborations. the ability to image the entire human body allows researchers to observe drug absorption, accumulation and elimination processes in all organs simultaneously.reduced radiation and scanning times expand pet imaging options for vulnerable groups such as children in impactful research and clinical studies. it also encourages the participation of healthy individuals in clinical trials and enables repeated scanning of patients to better understand disease progression and treatment effects, broadening medical research insights.“the collaboration between the university of sydney, the national imaging facility and northern sydney local health district demonstrates the power of partnerships in driving innovation,” said professor mark scott, vice-chancellor and president of the university of sydney.“this facility shows what can be achieved when leading institutions join forces to advance healthcare and research capabilities. we are not only improving the health of patients today, but also utilising this technology to fast-track new discoveries for the future.”australian national total body pet facility a game changer in medical imaging.one such study is examining how the molecule oxytocin impacts the brain and body when delivered to humans. oxytocin is one of the most important natural chemicals in the brain that guides social behaviour. when administered, research shows it can improve social understanding and may have benefits to support people with schizophrenia and autism. however, it is a mystery about where oxytocin is absorbed and the circuits it impacts in the brain and body to cause its effects in humans. using the tb pet scanner, a team led by the university of sydney’s professor adam guastella, will see in real-time the brain and body circuits impacted by oxytocin after its delivery intranasally or by intravenous injection. this has the potential to change fundamental knowledge of the biology of human social behaviour and could lead to a range of new therapies. the new facility forms part of sydney imaging, the university of sydneys core research facility for biomedical imaging. as a nationally significant research platform, it is also a flagship of the national imaging facility (nif), through the australian government department of education’s national collaborative research infrastructure strategy (ncris).governing board chair of the national imaging facility, professor margaret harding, said the nif’s investment of $8m in the australian national total body pet facility was its largest to date, and represented australias largest single investment in molecular imaging, underpinning research that is of high priority in reducing australia’s burden of disease.“the facility is a unique national asset which will revolutionise australia’s capacity to attract and support research and industry undertaking clinical trials for the development of new pharmaceuticals and medical products to improve health outcomes for australia,” professor harding said.the australian national total body pet facility will operate under an equal time-share arrangement between clinical use and research, ensuring five day per week open access for all researchers throughout australia.speaking to patient benefits, chief executive of the northern sydney local health district, adjunct professor anthony schembri, said: “royal north shore hospital and northern sydney local health district have a proud history of delivering world-class imaging and care to improve patient outcomes.“we are extremely honoured to be hosting this australian-first where patients can receive world class care, and researchers can use the scanner for clinical research which may translate into improving patient care in the future.”the university’s contribution to the new facility is underpinned by a bequest made by william chapman who left the majority of his estate as a gift dedicated to cancer research at the university of sydney. his legacy is set to have an enormous impact on cancer research and on the survival and quality of life of patients.the university of sydney’s professor emma johnston, deputy vice-chancellor (research), said: “the combined clinical and research arrangements for this amazing medical imaging technology and its location in a bustling hub of activity at royal north shore hospital will foster collaboration among researchers, healthcare providers, policymakers, and industry leaders to fast-track innovation in research translation.”more informationfor more information about the australian national total body pet facility, including capabilities and bookings for research use visit the sydney imaging website.image: ribbon cutting ceremony at royal north shore hospital with l to r: emma johnston, katie ockenden, mark scott (the university of sydney), anthony schembri,  alison zecchin (northern sydney local health district), simon ringer, robyn ward (the university of sydney), margaret harding (national imaging facility), steven meikle, rebeca gonzalez (the university of sydney), dale bailey (royal north shore hospital), sarah flaim (national imaging facility), fernando calamante (the university of sydney), heather gough (royal north shore hospital), paul roach (royal north shore hospital), wotjek goscinski (national imaging facility), and trevor danos (northern sydney local health district). .
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